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Conclusions Our study provides a blueprint for systematic proactive experimental evaluation of missense variant effects on human enzymes using cell-based models, including experimental modeling of how the impact of variants depends on therapeutic context

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Pernomian L, Duarte-Silva M, de Barros Cardoso CR

Rajala N, Gerhold JM, Martinsson P, et al

Study on purification of stem bromelain by nano-TiO2 and ultrafiltration

Oncotarget 6 , 97289739 (2015)